FOUNDATIONS SERIES · 2 min read

Epigenetics and Inherited Trauma

across generations through changes in gene expression — your nervous system may be
N
Noah Wickliffe, M.S.
Founder, MyoSport Inc. · Cal Crew '93 · Exercise Physiology

responding to wounds inflicted before you were born.

T H E S TO RY


COMPOSITE


PORTRAIT


W H AT T H E R E S E A R C H T E L L S U S

Epigenetic research has demonstrated that traumatic experiences alter gene expression through DNA methylation and histone modification — and these changes can be transmitted to subsequent generations (Lehrner & Yehuda, 2018). In Native American populations, researchers have identified epigenetic markers associated with historical trauma that persist across generations and contribute to present-day health disparities. Holocaust survivor offspring show altered cortisol metabolism and stress reactivity traceable to parental exposure (Yehuda et al., 2016). The mechanism operates through modifications to specific genes: NR3C1, which regulates cortisol receptors; FKBP5, which modulates stress response; and genes governing inflammatory pathways. A parent's trauma exposure can methylate these genes in ways that alter their expression in offspring — effectively passing a "stress-ready" biological setting to the next generation. The child inherits not the memory of trauma but the physiological preparation for it. There is also evidence that positive traits may transmit epigenetically. Parental experiences of meaningmaking, resilience practices, and sustained physical activity may produce favorable epigenetic modifications

— suggesting that the integration work one generation does may benefit the next.

HOW


SPORTSFLOW


MEASURES


AND


HELPS


SportsFlow doesn't distinguish between personal and inherited trauma — because the nervous system doesn't either. The Coherence Score tracks stress reactivity regardless of its origin. The Zen Score measures regulation capacity. The Flow Score tracks whether sustained practice is producing favorable changes. For people like River, the data provides a measurable baseline and a way to track whether exercise and contemplative practices are counteracting inherited programming — protecting not just this generation but potentially the next.

[1] Lehrner, A. & Yehuda, R. (2018). Cultural trauma and epigenetic inheritance. Development and Psychopathology, 30(5), 1763–1777. [2] Yehuda, R. et al. (2016). Holocaust exposure induced intergenerational effects on FKBP5 methylation. Biological Psychiatry, 80(5), 372–380. [3] Szyf, M. (2008). The social environment and the epigenome. Environmental Molecular Mutagenesis, 49, 46–60.

SPORTSFLOW.AI Know what you carry. Choose what you pass forward.

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